GARCINIA CAMBOGIA GARCINIA CAMBOGIA, ALSO KNOWN AS GARCINIA GUMMI-GUTTA, IS GROW IN SOUTHEASTERN ASIA, AND WEST AND CENTRAL AFRICA. THE FRUIT LOOKS LIKE A YELLOWISH, GREENISH OR REDDISH PUMPKIN WHICH IS ALSO COMMONLY KNOWN AS GAMBOOGE. IN THE INDIAN AYURVEDIC MEDICINE, "SOUR" FLAVORS ARE TOLDSAID TO ACTIVATE DIGESTION. IN THE AREAS WHERE IT IS CONSUMED, GARCINIA CAMBOGIA IS CONSIDERED TO BE EFFECTIVE IN MAKING MEALS MORE "FILLING" AND THEREFORE HELPING PEOPLE FEEL MORE SATIATED. THE RESEARCHERS HAVE STUDIED GARCINIA CAMBOGIA FOR YEARS, AND IT IS KNOWN THAT THE KEY INGREDIENT OF GARCINIA CAMBOGIA IS HCA.(HYDROXY CITRIC ACID). GREEN TEA GREEN TEA EXTRACT CONTAINS NUMEROUS COMPOUNDS, INCLUDING POLYPHENOLS AND CATECHINS, THAT PROVIDE POTENT ANTIOXIDANT BENEFITS. ONE CATECHIN IN PARTICULAR, EGCG, HAS DEMONSTRATED EXTRAORDINARY FREE RADICAL QUENCHING POWER IN LABORATORY STUDIES. IN NON-CLINICAL STUDIES, EGCG HAS ALSO BEEN SHOWN TO BE PROTECTIVE AGAINST CHEMICAL AND ENVIRONMENTAL ASSAULT ON TISSUES AND HELPS TO SUPPORT HEALTHY CELL CYCLE REGULATION. GREEN TEA IS TO BE USED WITH A PROGRAM OF REDUCED INTAKE OF DIETARY CALORIES AND INCREASED PHYSICAL ACTIVITY (IF POSSIBLE) TO HELP IN WEIGHT MANAGEMENT. GLUCOMANNAN GLUCOMANNAN HELPS TO LOWER CHOLESTEROL LEVELS BY REDUCING CHOLESTEROL ABSORPTION FROM THE GASTROINTESTINAL TRACT. GLUCOMANNAN IS A BULK-FORMING LAXATIVE, PROMOTE BOWEL MOVEMENTS BY INCREASING BULK VOLUME AND WATER CONTENT, AND PROVIDES GENTLE RELIEF OF CONSTIPATION AND/OR IRREGULARITY. GREEN COFFEE BEAN EXTRACT GREEN COFFEE BEAN EXTRACT IS AN UNROASTED, DRIED, NATURAL COFFEE BEAN. ROASTING COFFEE TRANSFORMS THE CHEMICAL AND PHYSICAL PROPERTIES OF GREEN COFFEE BEANS, TURNING THEM INTO COMMON COFFEE PRODUCTS. THE ROASTING PROCESS PRODUCES THE CHARACTERISTIC FLAVOUR OF COFFEE AS THE GREEN COFFEE BEANS CHANGE IN COLOR, TASTE, SMELL AND DENSITY. ROASTING ALSO MAKES THE COFFEE BEAN MORE UNSTABLE. AS A RESULT, IT CAN BECOME RANCID EASILY. UNROASTED GREEN COFFEE BEAN EXTRACT IS A NEW INGREDIENT ON THE MARKET. IT HAS STRONG ANTI-OXIDANT PROPERTIES, SIMILAR TO OTHER NATURAL ANTI-OXIDANTS LIKE GREEN TEA AND GRAPE SEED EXTRACT. DURATION OF USE CONSULT A HEALTH CARE PRACTITIONER FOR USE BEYOND 12 WEEKS. CAUTIONS AND WARNINGS CONSULT A HEALTH CARE PRACTITIONER PRIOR TO USE IF YOU HAVE A LIVER DISORDER OR DEVELOP SYMPTOMS OF LIVER TROUBLE. CONSULT A HEALTH CARE PRACTITIONER PRIOR TO USE IF YOU ARE PREGNANT OR BREASTFEEDING. CONSULT A HEALTH CARE PRACTITIONER PRIOR TO USE IF YOU HAVE AN IRON DEFICIENCY. GARCINIA CAMBOGIA CASTELLUCCIO C, PAGANGA G, MELIKIAN N, BOLWELL GP, PRIDHAM J, SAMPSON J, RICE-EVANS C. ANTIOXIDANT POTENTIAL OF INTERMEDIATES IN PHENYLPROPANOID METABOLISM IN HIGHER PLANTS. FEBS LETTERS 1995;368(1):188-192. DELLALIBERA O, LEMAIRE B AND LAFAY S. SVETOL�, GREEN COFFEE EXTRACT, INDUCES WEIGHT LOSS AND INCREASES LEAN TO FAT RATIO IN VOLUNTEERS WITH OVERWEIGHT PROBLEMS. PHYTOTHERAPIE 2006;4(4):194�197. KOZUMA K, TSUCHIYA S, KOHORI J, HASE T AND TOKIMITSU I. ANTIHYPERTENSIVE EFFECT OF GREEN COFFEE BEAN EXTRACT ON MILDLY HYPERTENSIVE SUBJECTS. HYPERTENSION RESEARCH: OFFICIAL JOURNAL OF THE JAPANESE SOCIETY OF HYPERTENSION 2005;28(8):711-718. MUBARAK A, BONDONNO CP, LIU AH, CONSIDINE MJ, RICH L, MAS E, CROFT KD, HODGSON JM. ACUTE EFFECTS OF CHLOROGENIC ACID ON NITRIC OXIDE STATUS, ENDOTHELIAL FUNCTION, AND BLOOD PRESSURE IN HEALTHY VOLUNTEERS: A RANDOMIZED TRIAL. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2012;60:9130-9136. THOM E. THE EFFECT OF CHLOROGENIC ACID ENRICHED COFFEE ON GLUCOSE ABSORPTION IN HEALTHY VOLUNTEERS AND ITS EFFECT ON BODY MASS WHEN USED LONG-TERM IN OVERWEIGHT AND OBESE PEOPLE. THE JOURNAL OF INTERNATIONAL MEDICAL RESEARCH 2007;35(6):900-908. USDA 2013: UNITED STATES DEPARTMENT OF AGRICULTURE, AGRICULTURAL RESEARCH SERVICE, NATIONAL GENETIC RESOURCES PROGRAM. GERMPLASM RESOURCES INFORMATION NETWORK (GRIN). [INTERNET]. NATIONAL GERMPLASM RESOURCES LABORATORY, BELTSVILLE (MD). [COFFEA ARABICA L. LAST UPDATED 2013 JANUARY 27] AND [COFFEA CANEPHORA PIERRE EX A. FROEHNER. LAST UPDATED 2013 JANUARY 27]. WATANABE T, ARAI Y, MITSUI Y, KUSAURA T, OKAWA W, KAJIHARA Y, SAITO I. THE BLOOD PRESSURE-LOWERING EFFECT AND SAFETY OF CHLOROGENIC ACID FROM GREEN COFFEE BEAN EXTRACT IN ESSENTIAL HYPERTENSION. CLINICAL AND EXPERIEMNTAL HYPERTENSION 2006;28(5):439-449. GREEN TEA CAMARGO AE, DAGUER DA, BARBOSA DS. GREEN TEA EXERTS ANTIOXIDANT ACTION IN VITRO AND ITS CONSUMPTION INCREASES TOTAL SERUM ANTIOXIDANT POTENTIAL IN NORMAL AND DYSLIPIDEMIC SUBJECTS. NUTRITION RESEARCH 2006;26:626-631. CHANTRE P, LAIRON D. RECENT FINDINGS OF GREEN TEA EXTRACT AR25 (EXOLISE) AND ITS ACTIVITY FOR THE TREATMENT OF OBESITY. PHYTOMEDICINE 2002;9(1):3-8. COIMBRA S, CASTRO E, ROCHA-PEREIRA P, REBELO I, ROCHA S, SANTOS-SILVA A. THE EFFECT OF GREEN TEA IN OXIDATIVE STRESS. CLINICAL NUTRITION 2006;25(5):790-796. COOPER MJ, COCKELL KA, L'ABBE MR. THE IRON STATUS OF CANADIAN ADOLESCENTS AND ADULTS: CURRENT KNOWLEDGE AND PRACTICAL IMPLICATIONS. CANADIAN JOURNAL OF DIETETIC PRACTICE AND RESEARCH 2006;67(3):130-138. DULLOO AG, DURET C, ROHRER D, GIRARDIER L, MENSI N, FATHI M, CHANTRE P, VANDERMANDER J. EFFICACY OF A GREEN TEA EXTRACT RICH IN CATECHIN POLYPHENOLS AND CAFFEINE IN INCREASING 24-H ENERGY EXPENDITURE AND FAT OXIDATION IN HUMANS. AMERICAN JOURNAL OF CLINICAL NUTRITION 1999;70(6):1040-1045. GLUCOMANNAN ARVILL A, BODIN L. EFFECT OF SHORT-TERM INGESTION OF KONJAC GLUCOMANNAN ON SERUM CHOLESTEROL IN HEALTHY MEN. AM J CLIN NUTR. 1995 MAR;61(3):585-9. BERARDI RR, DESIMONE EM, NEWTON GD, OSZKO MA, POPOVICH NG, ROLLINS CJ, SHIMP LA, TIETZE KJ, EDITORS. HANDBOOK OF NONPRESCRIPTION DRUGS: AN INTERACTIVE APPROACH TO SELF-CARE, 13TH EDITION. WASHINGTON (DC): AMERICAN PHARMACEUTICAL ASSOCIATION; 2002. CHEN HL, CHENG HC, LIU YJ, LIU SY, WU WT. 2006. KONJAC ACTS AS A NATURAL LAXATIVE BY INCREASING STOOL BULK AND IMPROVING COLONIC ECOLOGY IN HEALTHY ADULTS. NUTRITION 22:1112-1119. CHEN HL, CHENG HC, WU WT, LIU YJ, LIU SY. 2008. SUPPLEMENTATION OF KONJAC GLUCOMANNAN INTO A LOW-FIBRE CHINESE DIET PROMOTED BOWEL MOVEMENT AND IMPROVED COLONIC ECOLOGY IN CONSTIPATED ADULTS: A PLACEBO-CONTROLLED, DIET CONTROLLED TRIAL. JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION 27:102-108. CHEN HL, SHEU WH, TAI TS, LIAW YP, CHEN YC. KONJAC SUPPLEMENT ALLEVIATED HYPERCHOLESTEROLEMIA AND HYPERGLYCEMIA IN TYPE 2 DIABETIC SUBJECTS--A RANDOMIZED DOUBLE-BLIND TRIAL. J AM COLL NUTR. 2003 FEB;22(1):36-42. CHUA M, BALDWIN TC, HOCKING TJ, CHAN K. 2010. TRADITIONAL USES AND POTENTIAL HEALTH BENEFITS OF AMORPHOPHALLUS KONJAC K. KOCH EX N.E.BR. JOURNAL OF ETHNOPHARMACOLOGY 128(2):268-278. EFSA 2009: EUROPEAN FOOD SAFETY AUTHORITY. 2009. EFSA PANEL ON DIETETIC PRODUCTS, NUTRITION AND ALLERGIES; SCIENTIFIC OPINION ON THE SUBSTANTIATION OF HEALTH CLAIMS RELATED TO GLUCOMANNAN AND MAINTENANCE OF NORMAL BLOOD CHOLESTEROL CONCENTRATIONS (ID 836, 1560) PURSUANT TO ARTICLE 13(1) OF REGULATION (EC) NO 1924/2006 ON REQUEST FROM THE EUROPEAN COMMISSION. EFSA JOURNAL 7(9): 1258. DOI:10.2903/J.EFSA.2009.1258. AVAILABLE FROM: WWW.EFSA.EUROPA.EU. GREEN COFFEE BEAN EXTRACT CASTELLUCCIO C, PAGANGA G, MELIKIAN N, BOLWELL GP, PRIDHAM J, SAMPSON J, RICE-EVANS C. ANTIOXIDANT POTENTIAL OF INTERMEDIATES IN PHENYLPROPANOID METABOLISM IN HIGHER PLANTS. FEBS LETTERS 1995;368(1):188-192. DELLALIBERA O, LEMAIRE B AND LAFAY S. SVETOL�, GREEN COFFEE EXTRACT, INDUCES WEIGHT LOSS AND INCREASES LEAN TO FAT RATIO IN VOLUNTEERS WITH OVERWEIGHT PROBLEMS. PHYTOTHERAPIE 2006;4(4):194�197. KOZUMA K, TSUCHIYA S, KOHORI J, HASE T AND TOKIMITSU I. ANTIHYPERTENSIVE EFFECT OF GREEN COFFEE BEAN EXTRACT ON MILDLY HYPERTENSIVE SUBJECTS. HYPERTENSION RESEARCH: OFFICIAL JOURNAL OF THE JAPANESE SOCIETY OF HYPERTENSION 2005;28(8):711-718. MUBARAK A, BONDONNO CP, LIU AH, CONSIDINE MJ, RICH L, MAS E, CROFT KD, HODGSON JM. ACUTE EFFECTS OF CHLOROGENIC ACID ON NITRIC OXIDE STATUS, ENDOTHELIAL FUNCTION, AND BLOOD PRESSURE IN HEALTHY VOLUNTEERS: A RANDOMIZED TRIAL. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2012;60:9130-9136. THOM E. THE EFFECT OF CHLOROGENIC ACID ENRICHED COFFEE ON GLUCOSE ABSORPTION IN HEALTHY VOLUNTEERS AND ITS EFFECT ON BODY MASS WHEN USED LONG-TERM IN OVERWEIGHT AND OBESE PEOPLE. THE JOURNAL OF INTERNATIONAL MEDICAL RESEARCH 2007;35(6):900-908. USDA 2013: UNITED STATES DEPARTMENT OF AGRICULTURE, AGRICULTURAL RESEARCH SERVICE, NATIONAL GENETIC RESOURCES PROGRAM. GERMPLASM RESOURCES INFORMATION NETWORK (GRIN). [INTERNET]. NATIONAL GERMPLASM RESOURCES LABORATORY, BELTSVILLE (MD). [COFFEA ARABICA L. LAST UPDATED 2013 JANUARY 27] AND [COFFEA CANEPHORA PIERRE EX A. FROEHNER. LAST UPDATED 2013 JANUARY 27]. WATANABE T, ARAI Y, MITSUI Y, KUSAURA T, OKAWA W, KAJIHARA Y, SAITO I. THE BLOOD PRESSURE-LOWERING EFFECT AND SAFETY OF CHLOROGENIC ACID FROM GREEN COFFEE BEAN EXTRACT IN ESSENTIAL HYPERTENSION. CLINICAL AND EXPERIEMNTAL HYPERTENSION 2006;28(5):439-449. This page is not intended to be a comprehensive review of the medicinal ingredient.