IMPORTANCE OF MAGNESIUM MAGNESIUM IS BEST KNOWN AS THE ESSENTIAL NUTRIENT FOR THE FORMATION OF HEALTHY BONES AND TEETH. HOWEVER THIS MINERAL IS AN ESSENTIAL MINERAL NEEDED FOR MORE THAN 300 ENZYMATIC REACTIONS IN THE BODY. IT IS ACTING AS A MAIN ROLE FOR THE PROTEIN AND FATTY ACID FORMATION, ACTIVATING B VITAMINS, SUPPORTING MUSCLE ACTIVITY, NERVE TRANSMISSION, RELAXING BLOOD VESSELS, CLOTTING BLOOD, TEMPERATURE REGULATION AND ENSURING INTESTINAL MOBILITY ALSO CALLED BOWEL MOVEMENTS. SINCE MAGNESIUM RELAXES MUSCLES AND NERVES, MAGNESIUM SUPPLEMENTATION CAN HELP WITH MANY CONDITIONS FROM HIGH BLOOD PRESSURE, IRREGULAR HEARTBEAT OR HEART PALPITATIONS, TO INSOMNIA, ANXIETY AND DEPRESSION TO FIBROMYALGIA, OSTEOPOROSIS AND LEG CRAMPS AT NIGHT OR FOLLOWING EXERCISE. MAGNESIUM DEFICIENCY IS NOT THE RARE SYMPTOMS IN MODERN DAYS DUE TO THE CONSUMPTION OF PROCESSED FOODS AND THE DEPLETION OF MAGNESIUM FROM AGRICULTURAL SOILS. MAGNESIUM BISGLYCINATE MAGNESIUM BISGLYCINATE IS MAGNESIUM CHELATED TO THE AMINO ACID GLYCINE. THE WORD, CHELATE COMES FROM THE GREEK WORD �CHELE� WHICH MEANS CLAW. CHELATE MEANS �TO GRAB� OR �TO BIND� ESPECIALLY THE INTERACTION OF A METAL ION AND A SINGLE MOLECULE IS CALLED �CHELATION�. THE COMMONLY AVAILABLE MINERALS ARE OFTEN FOUND AS THE CHELATED FORM WITH INORGANIC SALT FORMS LIKE CHLORIDES, CARBONATES OR SULFATES. CHELATORS IN NUTRITIONAL SUPPLEMENTS ARE OFTEN INCLUDE AMINO ACIDS, ORGANIC ACIDS, PROTEINS, AND OCCASIONALLY MORE COMPLICATED CHEMICALS. THE BEST MAGNESIUM WILL BE THE ONE WHICH DOESN�T BREAK DOWN IN THE DIGESTIVE PROCESS AND CAN BE ABSORBED IN THE INTESTINAL (GUT) WALL AND FURTHER INTO THE BLOOD STREAM. MANY RESEARCHERS FOUND THAT AMINO ACID CHELATE MINERALS ARE BEST FOR ITS BIOAVAILABILITY. OTHER FORMS OF MAGNESIUM CAN REACH THE TARGET CELLS, HOWEVER, THE ABSORPTION RATE IS NOT LIKE WITH THE AMINO ACID CHELATED (EXPECIALLY BIS-GLYCINATE/ GLYCINATE CHELATED) MAGNESIUMS. THE BISGLYCINATE FORM OF MAGNESIUM PASSES INTO THE CELL VIA HUMAN BODY�S NATURAL AMINO ACID TRANSPORTATION. MAGNESIUM BISGLYCINATE HAS BEEN SHOWN TO CROSS THE BLOOD BRAIN BARRIER WHICH MAKES IT AN EXCELLENT CHOICE FOR AIDING THOSE WITH DEPRESSION AND/OR ANXIETY, OR MIGRAINE HEADACHES. OTHER COMMONLY AVAILABLE FORMS OF MAGNESIUM (MAGNESIUM OXIDE, CITRATES AND OTHERS) ARE OFTEN CAUSING DIARRHEA- BECAUSE OF POOR ABSORPTIONS. MAGNESIUM BISGLYCINATE RARELY CAUSE DIARRHEA AND FOUR TIMES MORE ABSORBED THAN CITRATE FORMS OF MAGNESIUM ALBION 2004A: MAGNESIUM: A ROLE IN THE THERAPY FOR ASTHMA. ALBION RESEARCH NOTES 2004;13(3) ALBION 2003B: MAGNESIUM - CLINICAL AND HEALTH BENEFITS STILL WITHOUT LIMITS. ALBION RESEARCH NOTES 2003;12(3) ALBION 1997B: MAGNESIUM: MINERAL LINK TO ENERGY. ALBION RESEARCH NOTES 1997;6(1) BURGESS E, LEWANCZUK R, BOLLI P, CHOCKALINGAM A, CUTLER H, TAYLOR G, HAMET P. LIFESTYLE MODIFICATIONS TO PREVENT AND CONTROL HYPERTENSION. 6. RECOMMENDATIONS ON POTASSIUM, MAGNESIUM AND CALCIUM. CANADIAN HYPERTENSION SOCIETY, CANADIAN COALITION FOR HIGH BLOOD PRESSURE PREVENTION AND CONTROL, LABORATORY CENTRE FOR DISEASE CONTROL AT HEALTH CANADA, HEART AND STROKE FOUNDATION OF CANADA. THE CANADIAN MEDICAL ASSOCIATION JOURNAL 1999;160(9):S35-45. FIROZ M, GRABER M. BIOAVAILABILITY OF US COMMERCIAL MAGNESIUM PREPARATIONS. MAGNESIUM RESEARCH 2001;14(4):257-62. IOM 1997: INSTITUTE OF MEDICINE. STANDING COMMITTEE ON THE SCIENTIFIC EVALUATION OF DIETARY REFERENCE INTAKES, FOOD AND NUTRITION BOARD, INSTITUTE OF MEDICINE. DIETARY REFERENCE INTAKES FOR CALCIUM, PHOSPHOROUS, MAGNESIUM, VITAMIN D, AND FLUORIDE. WASHINGTON (DC): NATIONAL ACADEMIES PRESS; 1997. MEISEL P, SCHWAHN C, LUEDEMANN J, JOHN U, KROEMER HK, KOCHER T. MAGNESIUM DEFICIENCY IS ASSOCIATED WITH PERIODONTAL DISEASE. JOURNAL OF DENTAL RESEARCH 2005;84(10):937-941. This page is not intended to be a comprehensive review of the medicinal ingredient.