Even now, your liver is hard at work filtering toxins out of your body, a process in which the liver itself can become collateral damage. With a 2,000-year history as a traditional herbal remedy, Milk Thistle provides potent herbal support to help protect and support the liver. Holista® Milk Thistle is concentrated and standardized to 60% silymarin for maximum benefits. Traditional Herbal Medicine to Protect the Liver: A wide array of health benefits Milk Thistle is one of the most trusted and well-researched herbs for liver support on the market. Here are a few of the ways it promotes whole body health: Protects the liver from damage Supports the liver?s natural detoxification mechanisms Provides antioxidant support Heading The liver is a highly specialized organ that is designed to deal with metabolic waste—the normal byproducts of your body’s functions—but even this sophisticated filtration system needs a hand sometimes. Because toxins are constantly cycling through the liver before being excreted, they can cause damage to the liver itself.1 Also, excessive environmental toxins can overburden the liver, impairing its function and causing damage.2 Milk Thistle is a gentle, safe, yet effective way to support and protect the liver. The antioxidants in Milk Thistle seed help support the liver as it neutralizes toxins that can damage tissues while the active compound, silymarin, protects the liver in order to allow for cellular renewal. 3 Studies show that silymarin may help protect the structural integrity of cellular membranes against toxic exposure.4 Research supports the use of Milk Thistle to improve liver health, helping restore liver function after damage caused by alcohol or toxic exposure.5,6,7 Heading Your liver doesn’t just process nutrients after they’ve been digested; it actually plays a big role in digestion itself. The liver produces bile—up to a litre a day—which helps break down fats so your body can absorb them.8 Because bile helps with the absorption of fats, it can help make fat-soluble nutrient such as vitamins A, D, E, and K more bioavailable. The body also uses bile as a handy way to excrete certain metabolic wastes, such as bilirubin, and as a defense mechanism to destroy bacteria in foods.9 When the liver is properly supported, it is better able to produce bile, improving your body’s ability to digest fat and excrete toxins.10 Keeping bile flowing freely also contributes to gallbladder health.11 Heading Silymarin has 10 times the antioxidant power of vitamin E.12 It reduces inflammation and helps the body make the antioxidant glutathione13, boosting production by 35%.14 Glutathione is the body’s most powerful weapon against toxic damage, an antioxidant that scoops up free radicals before they cause damage, and helps convert difficult to excrete fat soluble toxins into easily disposed of water soluble compounds.15 Your body makes glutathione, but poor diet, stress, aging, infections, medications, and environmental toxins can lead to serious depletion.16 By keeping toxins and inflammation in check, the liver plays an important role in immunity. Not only that, but white blood cells need glutathione to function. Silymarin also has its own antioxidant actions, and researchers call it “a powerful antioxidant herbal drug which can protect biological systems against the oxidative stress,” and it may be used in the prevention of free radical-related diseases.17 Heading Milk Thistle is very safe, and doesn’t have any significant side effects.18,19 Holista® Milk Thistle is standardized to 60% silymarin to ensure potency. The highly concentrated formula allows for maximum absorption and effectiveness. Each softgel contains: Milk Thistle (Silybum marianum) (seed) (standardized to 60% silymarin)................150 mg Non-medicinal ingredients: Softgel capsule (gelatin, glycerin, purified water), soybean oil, yellow beeswax, lecithin. Does Not Contain: Contains no artificial preservatives, colours or flavours; wheat or yeast. NPN 80003585 Recommended dosage (adults): 1 softgel 3 times daily with meals or as recommended by a physician. Consult a physician for prolonged use. Caution: Consult a physician prior to use if you have impaired liver function. Consult a physician if you experience persistent diarrhea. Do not use if you are pregnant or breastfeeding. Keep out of reach of children. Heading Holista offers quality dietary supplements, but is more than supplements. Holista vitamins, minerals, herbals and specialty supplements come in unique forms and formulas. Holista creams and topical products fill consumer needs that are not met by big name cosmetic products, and all our creams, lotions and shampoos are natural, hypoallergenic and gentle. You’re unique, so we’ve created a variety of uniquely formulated products for your health and beauty, inside and out. Holista® Take it for Life!TM Our product information specialists are waiting to answer any questions or comments you may have concerning Holista Milk Thistle. Call 1-800-204-4372. References: Murray, M.T., Pizzorno, J. (2012) The Encyclopedia of Natural Medicine. Simon & Schuster, Inc. New York, NY. Ibid Murray, M.T. (1995) The Healing Power of Herbs. Prima Publishing, Rocklin CA. Muriel, P., Mourelle M. (1990) Prevention by silymarin of membrane alterations in acute CCl4 liver damage. J Appl Toxicol, Aug;10(4):275-9. Murray, M.T. (1995) The Healing Power of Herbs. Prima Publishing, Rocklin CA. Pradhan, S.C., et al. (2006) Hepatoprotective herbal drug, silymarin from experimental pharmacology to clinical medicine. Indian J Med Res, Nov;124(5):491-504. Mourelle, M., Favari, L., Amezcua, J.L. (1988) Protection against thallium hepatotoxicity by silymarin. J Appl Toxicol, Oct;8(5):351-4. Murray, M.T., Pizzorno, J. (2012) The Encyclopedia of Natural Medicine. Simon & Schuster, Inc. New York, NY. Ibid Ibid Murray, M.T. (1995) The Healing Power of Herbs. Prima Publishing, Rocklin CA. Adzet, T. (1986) Polyphenolic compounds with biological and pharmacological activity. Herbs Spices Med Plants,1:167-184. Roozbeh, J. et al (2011) Comparative effects of silymarin and vitamin E supplementation on oxidative stress markers, and hemoglobin levels among patients on hemodialysis. Ren Fail, 33(2):118-23. Murray, M.T., Pizzorno, J. (2012) The Encyclopedia of Natural Medicine. Simon & Schuster, Inc. New York, NY. Ibid Ibid Asghar, Z., Masood, Z. (2008) Evaluation of antioxidant properties of silymarin and its potential to inhibit peroxyl radicals in vitro. Pak J Pharm Sci, Jul;21(3):249-54. Murray, M.T., Pizzorno, J. (2012) The Encyclopedia of Natural Medicine. Simon & Schuster, Inc. New York, NY. www.naturalstandard.com/databases/herbssupplements/milkthistle